We are looking for a Contract Budget Specialist to join the Project Finance team, responsible for end-to-end management of budgeting processes for our projects conducted in the United States and Latin America. The person in this role will be a key financial partner for project teams, sites, and internal departments, responsible for preparing, analyzing, and negotiating clinical trial budgets.
Responsibilities:
Preparation and updating of clinical trial budgets (site budgets) for US and Latin American sites, based on protocol assumptions and sponsor guidelines.
Conducting budget negotiations with sponsor representatives on behalf of Milestone One, the medical institution, and the investigator—from initial budget stage through final financial agreement.
Collaboration with Legal/Contracts in aligning the financial part of agreements with sites.
Analysis of costs and financial assumptions (patient visits, procedures, overhead costs, pass-through costs, etc.) and recommending optimal cost solutions.
Ensuring consistency of budgets with internal financial guidelines and sponsor requirements.
Input and maintenance of budgets and related financial data in CTMS and other internal tools.
Close collaboration with Project Managers, Project Finance, Clinical Operations, sites, and other stakeholders to ensure transparency and cost control.
Monitoring study changes (amendments) and updating budgets accordingly.
Preparation of financial summaries, analyses, and reports for internal use and, when needed, for the sponsor.
Requirements:
Professional experience in clinical research in CRO companies, pharmaceutical companies, or medical institutions involved in clinical trials.
Experience in preparing and negotiating clinical trial budgets (from the financial side, site/CRO/SMO perspective).
Strong knowledge of clinical trial cost structures (site fees, medical procedures, investigator fees, overhead, admin fees, pass-through costs, etc.).
Experience working with CTMS systems and advanced Excel skills.
Fluent English and Spanish.
Ability to independently conduct financial negotiations, assertiveness, strong communication skills, and high professional standards.
Attention to detail, analytical thinking, ability to manage multiple projects simultaneously, and meet deadlines. If you feel it is time to make your skills and knowledge visible within a developing company with true focus on its people, then Milestone One is the right choice for you!
Milestone One is a Site Enabling Services organization with global headquarters in Zug, Switzerland. We understand what clinical study sites need and our overall mission is to support sites in stronger study delivery.
PSI is a leading Contract Research Organization (CRO) with 30 years of experience in the pharmaceutical industry, originating in Switzerland as a privately owned, full-service firm. The company supports clinical trials across multiple countries and continents, managing comprehensive trial operations including investigator site identification, patient enrollment, monitoring, data integrity, and regulatory compliance. PSI is known for being highly selective about projects and delivering high-quality, timely services across a broad spectrum of therapeutic indications. The company also develops internal IT solutions with a focus on AI initiatives to support business processes and operations.
