Remote Jobs in South Carolina

Browse 12056 remote jobs available in South Carolina (SC).

Sobi

Manager Global Scientific Affairs

Sobi

Full-time
Remote1 weeks ago
Accelerant

Operations Specialist

Accelerant

Remote
Full-time
Remote1 weeks ago
Radiology Partners

Remote Evening Diagnostic Radiologist - Radiology Partners Saline Valley

Radiology Partners

Remote
Full-time
RemoteUSD 600,000 - 650,0001 weeks ago
Radiology Partners

Risk Manager

Radiology Partners

Remote
Full-time
RemoteUSD 130,000 - 140,0001 weeks ago
Montu

Patient Care - Registered Nurse - Afternoon Shift

Montu

Remote
Full-time
RemoteAUD 91,500 - 100,0001 weeks ago
Stretto, Inc.

Director of Sales, Research Suite

Stretto, Inc.

Full-time
RemoteUSD 100,000 - 120,0001 weeks ago
Maxana

Payments Systems Manager

Maxana

Remote
Full-time
Remote1 weeks ago
Hadley Designs

Director of Distributed Team Operations

Hadley Designs

Remote
Full-time
Remote1 weeks ago
Bjak

Recruiting Coordinator

Bjak

Remote
Full-time
Remote1 weeks ago
Johnson & Johnson

Associate Site Manager - Oncology - Western U.S.

Johnson & Johnson

Remote
Full-time
RemoteUSD 76,000 - 121,9001 weeks ago
Bjak

Entrepreneur in Residence

Bjak

Remote
Full-time
Remote1 weeks ago
Huzzle

Sales Development Representative (SDR) - AI SaaS

Huzzle

Remote
Full-time
Remote1 weeks ago
Bright Vision Technologies

Backend Developer – Go

Bright Vision Technologies

Remote
Full-time
RemoteUSD 100,000 - 150,0001 weeks ago
Inizio Partners Corp

Senior AWS Cloud Developer

Inizio Partners Corp

Full-time
Remote1 weeks ago
Radiology Partners

All Remote Overnight Teleradiologist – Emergency Radiology (Neuroradiology Prefe

Radiology Partners

Remote
Full-time
RemoteUSD 475,000 - 900,0001 weeks ago
Abbott

Territory Sales Manager

Abbott

Full-time
Remote1 weeks ago
Bjak

Entrepreneur in Residence

Bjak

Remote
Full-time
Remote1 weeks ago
Bjak

Senior Recruiter, Product & Engineering

Bjak

Remote
Full-time
Remote1 weeks ago
Johns Hopkins University

Research Data Analyst (Pediatrics)

Johns Hopkins University

Part-time
RemoteUSD 23.07 - 40.431 weeks ago
Radiology Partners

Remote Daytime General Radiologist - Radiology Partners Kentucky

Radiology Partners

Remote
Full-time
RemoteUSD 550,000 - 550,0001 weeks ago
Showing 24012420 of 12056 jobs

Remote Work in South Carolina

South Carolina's economic history is a story of remarkable transformation, from one of the most plantation-dependent colonial economies in the Americas to a modern state that has attracted more foreign direct investment per capita than almost anywhere in the country. The rice and indigo plantations of the Lowcountry, worked by enslaved African people — many brought directly from rice-growing regions of West Africa — made colonial South Carolina extraordinarily wealthy and shaped a plantation aristocracy whose cultural influence lingered long after the Civil War ended slavery.

Cotton replaced rice and indigo after Eli Whitney's gin made large-scale production economical, and the Upcountry piedmont became a major cotton-growing region through the nineteenth century. The cotton boom led to textile mills — South Carolina had more textile mills than any other Southern state by 1900 — and mill towns like Greenville, Spartanburg, and Rock Hill developed around the industry. The decline of American textile manufacturing in the late twentieth century hit South Carolina hard, but the state's aggressive industrial recruitment strategy turned adversity into opportunity.

BMW chose Spartanburg, South Carolina, as the location for its first North American manufacturing plant in 1992, beginning a wave of foreign automotive investment that transformed the Upstate region. Mercedes-Benz Vans, Volvo (with a plant near Berkeley County), and their respective supplier networks followed, along with Boeing, which built its second 787 Dreamliner final assembly plant in North Charleston in 2009 — the company's first aircraft manufacturing operation outside of the Pacific Northwest. General Electric operates large manufacturing facilities in the state.

The Mercedes-Benz Vans plant, Boeing's Charleston facility, and BMW's Spartanburg campus are now among the largest industrial employers in the state, and the supply chain networks around them have created thousands of additional jobs in precision manufacturing, logistics, and engineering services.

Charleston has emerged as a significant technology and financial services hub, attractwith a growing presence of companies like Blackbaud, Benefitfocus, and Automated Trading Desk. The city's historic beauty, warm climate, and water access make it highly attractive to professionals seeking an alternative to expensive coastal metros.

Remote work has been a significant driver of South Carolina's recent growth. The state has attracted remote workers from New York, New Jersey, and the Mid-Atlantic with its combination of no estate tax, warm climate, beautiful coastline, and increasingly good infrastructure. The Greenville-Spartanburg metro in particular has emerged as a remote work destination for professionals in technology, engineering, and finance.