Remote Jobs in South Carolina

Browse 11947 remote jobs available in South Carolina (SC).

PointClickCare

Sr. Customer Engagement Marketing Manager (Canada)

PointClickCare

Remote
Full-time
Remote or Mississauga1 weeks ago
Natera

Oncology Pathology Assist Temp Position

Natera

Remote
Full-time
US Remote1 weeks ago
Headspace

Psychiatric Nurse Practitioner, Part Time (1099 Contractor)

Headspace

Remote
Part-time
USAUSD 160,000 - 200,0001 weeks ago
The Cigna Group

Part Time Inpatient Telephonic Staff Pharmacist (Evenings / Overnight)

The Cigna Group

Remote
Part-time
USAUSD 108,000 - 182,0001 weeks ago
Natera

IOP/PSC Team Lead - Florida

Natera

Remote
Full-time
US Remote1 weeks ago
Zoom

AI Information Architect/ Content Strategist

Zoom

Remote
Full-time
Flexible / Remote1 weeks ago
Solana Foundation

Affiliate Manager

Solana Foundation

Full-time
Remote (US)1 weeks ago
Reddit

Staff People Integrations Engineer

Reddit

Remote
Full-time
Remote - United States1 weeks ago
Hightouch

Technical Account Manager, Enterprise (East)

Hightouch

Remote
Full-time
Remote (North America)1 weeks ago
Natera

Senior Clinical Research Associate

Natera

Remote
Full-time
US Remote1 weeks ago
Leidos

Supply Chain Risk Management Specialist

Leidos

Remote
Full-time
Flexible / Remote1 weeks ago
Leidos

Tier 1 Customer Service Representative

Leidos

Remote
Full-time
Flexible / Remote1 weeks ago
PointClickCare

Product Manager – Orders Management (Senior Care)

PointClickCare

Remote
Contract
Remote or Mississauga1 weeks ago
PointClickCare

Product Manager – Orders Management (Senior Care)

PointClickCare

Remote
Contract
Remote, USA1 weeks ago
GE Vernova

Customer Success Manager - Controls NAM (South Region)

GE Vernova

Remote
Full-time
Flexible / Remote1 weeks ago
C

Principal Product Manager - 11744

Coupa

Full-time
Flexible / Remote1 weeks ago
C

Instructional Designer - 11611

Coupa

Full-time
Flexible / Remote1 weeks ago
C

Principal Software Engineer - 11498

Coupa

Full-time
Flexible / Remote1 weeks ago
Tango

Staff Analytics Engineer

Tango

Full-time
RemoteUSD 160,000 - 190,0001 weeks ago
G

Sales Director - Enterprise (Loqate)

GBG

Full-time
Remote1 weeks ago
Showing 26412660 of 11947 jobs

Remote Work in South Carolina

South Carolina's economic history is a story of remarkable transformation, from one of the most plantation-dependent colonial economies in the Americas to a modern state that has attracted more foreign direct investment per capita than almost anywhere in the country. The rice and indigo plantations of the Lowcountry, worked by enslaved African people — many brought directly from rice-growing regions of West Africa — made colonial South Carolina extraordinarily wealthy and shaped a plantation aristocracy whose cultural influence lingered long after the Civil War ended slavery.

Cotton replaced rice and indigo after Eli Whitney's gin made large-scale production economical, and the Upcountry piedmont became a major cotton-growing region through the nineteenth century. The cotton boom led to textile mills — South Carolina had more textile mills than any other Southern state by 1900 — and mill towns like Greenville, Spartanburg, and Rock Hill developed around the industry. The decline of American textile manufacturing in the late twentieth century hit South Carolina hard, but the state's aggressive industrial recruitment strategy turned adversity into opportunity.

BMW chose Spartanburg, South Carolina, as the location for its first North American manufacturing plant in 1992, beginning a wave of foreign automotive investment that transformed the Upstate region. Mercedes-Benz Vans, Volvo (with a plant near Berkeley County), and their respective supplier networks followed, along with Boeing, which built its second 787 Dreamliner final assembly plant in North Charleston in 2009 — the company's first aircraft manufacturing operation outside of the Pacific Northwest. General Electric operates large manufacturing facilities in the state.

The Mercedes-Benz Vans plant, Boeing's Charleston facility, and BMW's Spartanburg campus are now among the largest industrial employers in the state, and the supply chain networks around them have created thousands of additional jobs in precision manufacturing, logistics, and engineering services.

Charleston has emerged as a significant technology and financial services hub, attractwith a growing presence of companies like Blackbaud, Benefitfocus, and Automated Trading Desk. The city's historic beauty, warm climate, and water access make it highly attractive to professionals seeking an alternative to expensive coastal metros.

Remote work has been a significant driver of South Carolina's recent growth. The state has attracted remote workers from New York, New Jersey, and the Mid-Atlantic with its combination of no estate tax, warm climate, beautiful coastline, and increasingly good infrastructure. The Greenville-Spartanburg metro in particular has emerged as a remote work destination for professionals in technology, engineering, and finance.