Remote Jobs in South Carolina

Browse 12006 remote jobs available in South Carolina (SC).

Sezzle

Junior Software Engineer with Accounting Experience (LATAM)

Sezzle

Remote
Full-time
RemoteUSD 1,500 - 4,0001 weeks ago
FamilyWell Health

Women's Mental Health Therapist - Texas

FamilyWell Health

Contract
Remote1 weeks ago
VirtusLab

Keen to join us

VirtusLab

Full-time
Remote1 weeks ago
Life360

Staff Data Scientist - Ads (AI Native)

Life360

Remote
Full-time
RemoteUSD 137,000 - 252,0001 weeks ago
RightMove Health

PRN Virtual MSK Physical Therapist (Compact State Preferred)

RightMove Health

Remote
Contract
Remote1 weeks ago
Backpack Healthcare

Outpatient Psychiatrist

Backpack Healthcare

Full-time
Remote1 weeks ago
Robots & Pencils

Payroll & Benefits Administrator

Robots & Pencils

Full-time
Remote1 weeks ago
ZutaCore

VP Sales of Europe

ZutaCore

Full-time
Remote1 weeks ago
Radiology Partners

Breast Imaging Radiologist - Radiology Associates of Hollywood

Radiology Partners

Remote
Full-time
RemoteUSD 500,000 - 500,0001 weeks ago
Epic

EdTech Conference Coordinator (Contract)

Epic

Remote
Contract
RemoteUSD 43 - 501 weeks ago
NVIDIA

Principal Platform Software Engineer - RAS

NVIDIA

Full-time
RemoteUSD 272,000 - 431,2501 weeks ago
Nebius

Operational Excellence Manager

Nebius

Remote
Full-time
Remote1 weeks ago
Indigo Consulting

Senior PAM Expert

Indigo Consulting

Remote
Full-time
Remote1 weeks ago
Lifelancer

Executive Director, Biotech Client Experience (Onboarding & Enablement) US

Lifelancer

Remote
Full-time
RemoteUSD 186,700 - 248,9001 weeks ago
IFS

Principal Platform Engineer || Agentic AI || Identity and Access Management

IFS

Full-time
Remote1 weeks ago
Samsara

Sales Engineer, Mid Market - TOLA

Samsara

Remote
Full-time
RemoteUSD 95,795 - 144,9001 weeks ago
Lifelancer

Services Engagement Manager - Development Cloud

Lifelancer

Remote
Full-time
RemoteUSD 85,000 - 170,0001 weeks ago
Prolific

Strategic Account Executive

Prolific

Remote
Full-time
(Remote) Seattle 1 weeks ago
Inflect

Account Director – AI & Infrastructure Providers - fully remote!

Inflect

Remote
Full-time
Remote1 weeks ago
Life360

Principal PM II, Location Platform & Quality

Life360

Remote
Full-time
RemoteUSD 178,500 - 261,5001 weeks ago
Showing 28012820 of 12006 jobs

Remote Work in South Carolina

South Carolina's economic history is a story of remarkable transformation, from one of the most plantation-dependent colonial economies in the Americas to a modern state that has attracted more foreign direct investment per capita than almost anywhere in the country. The rice and indigo plantations of the Lowcountry, worked by enslaved African people — many brought directly from rice-growing regions of West Africa — made colonial South Carolina extraordinarily wealthy and shaped a plantation aristocracy whose cultural influence lingered long after the Civil War ended slavery.

Cotton replaced rice and indigo after Eli Whitney's gin made large-scale production economical, and the Upcountry piedmont became a major cotton-growing region through the nineteenth century. The cotton boom led to textile mills — South Carolina had more textile mills than any other Southern state by 1900 — and mill towns like Greenville, Spartanburg, and Rock Hill developed around the industry. The decline of American textile manufacturing in the late twentieth century hit South Carolina hard, but the state's aggressive industrial recruitment strategy turned adversity into opportunity.

BMW chose Spartanburg, South Carolina, as the location for its first North American manufacturing plant in 1992, beginning a wave of foreign automotive investment that transformed the Upstate region. Mercedes-Benz Vans, Volvo (with a plant near Berkeley County), and their respective supplier networks followed, along with Boeing, which built its second 787 Dreamliner final assembly plant in North Charleston in 2009 — the company's first aircraft manufacturing operation outside of the Pacific Northwest. General Electric operates large manufacturing facilities in the state.

The Mercedes-Benz Vans plant, Boeing's Charleston facility, and BMW's Spartanburg campus are now among the largest industrial employers in the state, and the supply chain networks around them have created thousands of additional jobs in precision manufacturing, logistics, and engineering services.

Charleston has emerged as a significant technology and financial services hub, attractwith a growing presence of companies like Blackbaud, Benefitfocus, and Automated Trading Desk. The city's historic beauty, warm climate, and water access make it highly attractive to professionals seeking an alternative to expensive coastal metros.

Remote work has been a significant driver of South Carolina's recent growth. The state has attracted remote workers from New York, New Jersey, and the Mid-Atlantic with its combination of no estate tax, warm climate, beautiful coastline, and increasingly good infrastructure. The Greenville-Spartanburg metro in particular has emerged as a remote work destination for professionals in technology, engineering, and finance.