Remote Jobs in South Carolina

Browse 12664 remote jobs available in South Carolina (SC).

BSI

GQA Technical and Regulatory Reviewer

BSI

Full-time
RemoteToday
mercor

IP Expert - Patent Specialist

mercor

Remote
Full-time
RemoteUSD 85 - 120Today
Blackbird Health

Child and Adolescent Therapist VA License - LCSW, LPC, LMFT - Contract/1099

Blackbird Health

Remote
Contract
RemoteUSD 85 - 95Today
AbbVie

Sales Representative Gastroenterology (m/w/d) - Wirkung entfalten, Beziehungen s

AbbVie

Remote
Full-time
RemoteEUR 2,807 - 2,807Today
E

Senior Software Engineer, Full Stack

Evolve

Full-time
RemoteUSD 141,000 - 184,000Today
AMS Accelerate IT

Sales Development Representative - L3X3V8X8

AMS Accelerate IT

Remote
Full-time
RemoteToday
LexisNexis

Chief of Staff, Sales (Nexis Solutions)

LexisNexis

Remote
Full-time
RemoteUSD 130,200 - 241,800Today
The Hello Team

Remote Takeoff & Estimating Assistant (Electrical, Construction)

The Hello Team

Remote
Full-time
RemoteToday
Populate

Senior .NET Software Engineer (Remote: BD)

Populate

Remote
Full-time
RemoteToday
Human Interest

Manager, Operations

Human Interest

Remote
Full-time
RemoteUSD 75,000 - 90,000Today
CI

Senior Automotive Technical Advisor

COMPLEX International Recruitment Philippines Inc.

Full-time
RemoteToday
SB

Director, Channel Management, Greater Asia

Standard BioTools Singapore Pte. Ltd.

Full-time
RemoteToday
NTT DATA

Remote Bilingual Customer Care Associate (Moncton, NB, CA)

NTT DATA

Remote
Full-time
RemoteCAD 20 - 21Today
C

Domestic Sales Trainer

Citizens

Full-time
RemoteToday
mercor

Compliance Specialist - Fully Remote | Up to $110/hr

mercor

Remote
Contract
RemoteUSD 70 - 110Today
Agfa

Global Enterprise Solutions Architect - USA (Home based, US)

Agfa

Full-time
RemoteToday
Epiq

Bilingual Contact Center Agent

Epiq

Part-time
RemoteToday
Nagarro

Staff Consultant, Admin Operations

Nagarro

Remote
Full-time
RemoteToday
Arize AI

AI Sales Engineer, (EMEA)

Arize AI

Remote
Full-time
RemoteToday
Harbor

Junior Developer (Finance Systems)

Harbor

Remote
Full-time
RemoteToday
Showing 41–60 of 12664 jobs

Remote Work in South Carolina

South Carolina's economic history is a story of remarkable transformation, from one of the most plantation-dependent colonial economies in the Americas to a modern state that has attracted more foreign direct investment per capita than almost anywhere in the country. The rice and indigo plantations of the Lowcountry, worked by enslaved African people — many brought directly from rice-growing regions of West Africa — made colonial South Carolina extraordinarily wealthy and shaped a plantation aristocracy whose cultural influence lingered long after the Civil War ended slavery.

Cotton replaced rice and indigo after Eli Whitney's gin made large-scale production economical, and the Upcountry piedmont became a major cotton-growing region through the nineteenth century. The cotton boom led to textile mills — South Carolina had more textile mills than any other Southern state by 1900 — and mill towns like Greenville, Spartanburg, and Rock Hill developed around the industry. The decline of American textile manufacturing in the late twentieth century hit South Carolina hard, but the state's aggressive industrial recruitment strategy turned adversity into opportunity.

BMW chose Spartanburg, South Carolina, as the location for its first North American manufacturing plant in 1992, beginning a wave of foreign automotive investment that transformed the Upstate region. Mercedes-Benz Vans, Volvo (with a plant near Berkeley County), and their respective supplier networks followed, along with Boeing, which built its second 787 Dreamliner final assembly plant in North Charleston in 2009 — the company's first aircraft manufacturing operation outside of the Pacific Northwest. General Electric operates large manufacturing facilities in the state.

The Mercedes-Benz Vans plant, Boeing's Charleston facility, and BMW's Spartanburg campus are now among the largest industrial employers in the state, and the supply chain networks around them have created thousands of additional jobs in precision manufacturing, logistics, and engineering services.

Charleston has emerged as a significant technology and financial services hub, attractwith a growing presence of companies like Blackbaud, Benefitfocus, and Automated Trading Desk. The city's historic beauty, warm climate, and water access make it highly attractive to professionals seeking an alternative to expensive coastal metros.

Remote work has been a significant driver of South Carolina's recent growth. The state has attracted remote workers from New York, New Jersey, and the Mid-Atlantic with its combination of no estate tax, warm climate, beautiful coastline, and increasingly good infrastructure. The Greenville-Spartanburg metro in particular has emerged as a remote work destination for professionals in technology, engineering, and finance.