Remote Jobs in South Dakota

Browse 12141 remote jobs available in South Dakota (SD).

Bjak

Assistant Recruitment Manager

Bjak

Remote
Full-time
Remote1 weeks ago
Labcorp

Accounts Receivable Specialist I - Remote

Labcorp

Remote
Full-time
Flexible / Remote1 weeks ago
Labcorp

Cytogenetics Analyst - US Remote

Labcorp

Remote
Full-time
Flexible / Remote1 weeks ago
Labcorp

Financial Assistance Program CSSR III- Remote

Labcorp

Remote
Full-time
Flexible / Remote1 weeks ago
Labcorp

Senior Employee Relations Manager

Labcorp

Remote
Full-time
Flexible / Remote1 weeks ago
CrowdStrike

Sales Specialist, Cloud Security (Remote, GBR)

CrowdStrike

Remote
Full-time
Flexible / Remote1 weeks ago
Natera

Training Specialist, PX & Patient Coordinators

Natera

Remote
Full-time
US Remote1 weeks ago
Precision AQ

Senior Account Executive - Healthcare Marketing

Precision AQ

Remote
Full-time
Remote, United States1 weeks ago
Human Interest

Senior Financial Analyst - Corporate FP&A

Human Interest

Remote
Full-time
United States, Remote1 weeks ago
Natera

Medical Science Liaison

Natera

Remote
Full-time
US Remote1 weeks ago
PointClickCare

Sr. Customer Engagement Marketing Manager (US)

PointClickCare

Remote
Full-time
Remote, USA1 weeks ago
PointClickCare

Sr. Customer Engagement Marketing Manager (Canada)

PointClickCare

Remote
Full-time
Remote or Mississauga1 weeks ago
Natera

Oncology Pathology Assist Temp Position

Natera

Remote
Full-time
US Remote1 weeks ago
Headspace

Psychiatric Nurse Practitioner, Part Time (1099 Contractor)

Headspace

Remote
Part-time
USAUSD 160,000 - 200,0001 weeks ago
The Cigna Group

Part Time Inpatient Telephonic Staff Pharmacist (Evenings / Overnight)

The Cigna Group

Remote
Part-time
USAUSD 108,000 - 182,0001 weeks ago
Natera

IOP/PSC Team Lead - Florida

Natera

Remote
Full-time
US Remote1 weeks ago
Zoom

AI Information Architect/ Content Strategist

Zoom

Remote
Full-time
Flexible / Remote1 weeks ago
Reddit

Staff People Integrations Engineer

Reddit

Remote
Full-time
Remote - United States1 weeks ago
Hightouch

Technical Account Manager, Enterprise (East)

Hightouch

Remote
Full-time
Remote (North America)1 weeks ago
Natera

Senior Clinical Research Associate

Natera

Remote
Full-time
US Remote1 weeks ago
Showing 23212340 of 12141 jobs

Remote Work in South Dakota

South Dakota occupies a unique place in the American economic landscape — a state of extreme geographic and economic contrasts, from the fertile James River lowlands to the arid Badlands, from the Black Hills gold country to the Missouri River reservoir system. Its economy is small by national standards but distinctive in its combination of agriculture, tourism, finance, and a surprisingly powerful position in the national credit card and banking industry.

Agriculture defines South Dakota's physical landscape and economic backbone. The state is a major producer of corn, soybeans, wheat, sunflowers, and cattle — its eastern half lies within the productive Corn Belt, while the western half transitions to range land and cattle ranching. South Dakota is consistently among the top five states in cattle production. The Sioux Falls metro, the state's largest city, has a significant meat processing sector, with Tyson Foods operating one of its largest beef processing facilities there.

The Black Hills, in the western part of the state, have been economically significant since gold was discovered there in 1874 by an expedition led by George Armstrong Custer. The Homestake Mine in Lead, which operated from 1877 to 2002, was the largest and deepest gold mine in the Western Hemisphere. The mine is now being converted to the Sanford Underground Research Facility, a world-class physics laboratory conducting experiments that require the rock shielding deep underground can provide.

Mount Rushmore and the Badlands National Park are South Dakota's most famous tourism draws, anchoring a tourism industry that brings millions of visitors annually to the Black Hills, Deadwood's casinos, and the annual Sturgis Motorcycle Rally — one of the largest motorcycle events in the world.

The credit card and banking industry has been one of South Dakota's most economically significant sectors since 1981, when the state eliminated usury laws capping interest rates, allowing credit card companies to relocate operations there and charge nationally. Citibank moved its credit card operations to Sioux Falls almost immediately, followed by Wells Fargo, Capital One, and dozens of other financial institutions. Today Sioux Falls is home to major credit card processing operations employing tens of thousands and managing billions in transactions daily.

Remote work has been relatively limited in South Dakota due to the rural nature of much of the state, but Sioux Falls — a genuine small city with strong infrastructure, low cost of living, and no state income tax — has positioned itself as an attractive destination for remote workers seeking Midwestern affordability with real urban amenities.