Remote Jobs in South Carolina

Browse 12021 remote jobs available in South Carolina (SC).

WRS Health

Client Success Manager

WRS Health

Remote
Full-time
Remote1 months ago
Prep Network

Prep Hoops Scout

Prep Network

Full-time
Remote1 months ago
Prep Network

Product Scores Specialist

Prep Network

Full-time
Remote1 months ago
Natera

Director, Field Translational Science — Oncology

Natera

Remote
Full-time
US Remote1 months ago
Pharmaceutical Strategies Group LLC

Marketing Content Writer

Pharmaceutical Strategies Group LLC

Remote
Full-time
Remote US Based1 months ago
Power Digital Marketing

Email Strategist

Power Digital Marketing

Remote
Full-time
Remote - Ecuador1 months ago
Power Digital Marketing

Email Strategist

Power Digital Marketing

Remote
Full-time
Remote - Costa Rica1 months ago
Power Digital Marketing

Email Strategist

Power Digital Marketing

Remote
Full-time
Remote - Argentina1 months ago
Power Digital Marketing

Email Strategist

Power Digital Marketing

Remote
Full-time
Remote - Colombia1 months ago
Natera

Senior Bioinformatics Scientist

Natera

Remote
Full-time
US Remote1 months ago
Reddit

Senior Staff Machine Learning Systems Engineer, Feed Relevance

Reddit

Remote
Full-time
Remote - United States1 months ago
Reddit

Senior Staff Machine Learning Systems Engineer, Indexing & Retrieval Search

Reddit

Remote
Full-time
Remote - United States1 months ago
24-MAG

Remote | Advanced Physics Problem Design Expert — $100–$125/hour

24-MAG

Remote
Full-time
RemoteUSD 100 - 1251 months ago
Paired

Tax Administrative Assistant for US-based company

Paired

Remote
Full-time
Remote1 months ago
goPro Consultancy Group ltd.

Data Quality/ETL Specialist - FULLY REMOTE - Employee in USD

goPro Consultancy Group ltd.

Full-time
Remote1 months ago
Prysmian Group

Hyperscale-Long Haul-Middle Mile Business Development

Prysmian Group

Remote
Full-time
Remote1 months ago
Libertex Group

Customer Success Officer

Libertex Group

Full-time
Remote1 months ago
Tutor Me Education

Virtual Teacher

Tutor Me Education

Remote
Contract
Remote1 months ago
Tutor Me Education

Virtual SPED Tutor

Tutor Me Education

Remote
Contract
Remote1 months ago
24-MAG

Remote | Applied Machine Learning Evaluation Consultant — Up to $100/hour

24-MAG

Remote
Full-time
RemoteUSD 100 - 1001 months ago
Showing 1190111920 of 12021 jobs

Remote Work in South Carolina

South Carolina's economic history is a story of remarkable transformation, from one of the most plantation-dependent colonial economies in the Americas to a modern state that has attracted more foreign direct investment per capita than almost anywhere in the country. The rice and indigo plantations of the Lowcountry, worked by enslaved African people — many brought directly from rice-growing regions of West Africa — made colonial South Carolina extraordinarily wealthy and shaped a plantation aristocracy whose cultural influence lingered long after the Civil War ended slavery.

Cotton replaced rice and indigo after Eli Whitney's gin made large-scale production economical, and the Upcountry piedmont became a major cotton-growing region through the nineteenth century. The cotton boom led to textile mills — South Carolina had more textile mills than any other Southern state by 1900 — and mill towns like Greenville, Spartanburg, and Rock Hill developed around the industry. The decline of American textile manufacturing in the late twentieth century hit South Carolina hard, but the state's aggressive industrial recruitment strategy turned adversity into opportunity.

BMW chose Spartanburg, South Carolina, as the location for its first North American manufacturing plant in 1992, beginning a wave of foreign automotive investment that transformed the Upstate region. Mercedes-Benz Vans, Volvo (with a plant near Berkeley County), and their respective supplier networks followed, along with Boeing, which built its second 787 Dreamliner final assembly plant in North Charleston in 2009 — the company's first aircraft manufacturing operation outside of the Pacific Northwest. General Electric operates large manufacturing facilities in the state.

The Mercedes-Benz Vans plant, Boeing's Charleston facility, and BMW's Spartanburg campus are now among the largest industrial employers in the state, and the supply chain networks around them have created thousands of additional jobs in precision manufacturing, logistics, and engineering services.

Charleston has emerged as a significant technology and financial services hub, attractwith a growing presence of companies like Blackbaud, Benefitfocus, and Automated Trading Desk. The city's historic beauty, warm climate, and water access make it highly attractive to professionals seeking an alternative to expensive coastal metros.

Remote work has been a significant driver of South Carolina's recent growth. The state has attracted remote workers from New York, New Jersey, and the Mid-Atlantic with its combination of no estate tax, warm climate, beautiful coastline, and increasingly good infrastructure. The Greenville-Spartanburg metro in particular has emerged as a remote work destination for professionals in technology, engineering, and finance.