Remote Jobs in South Carolina

Browse 12021 remote jobs available in South Carolina (SC).

24x7 Direct

Digital Marketing Assistant & Social Media Manager

24x7 Direct

Remote
Full-time
RemotePHP 35,000 - 35,0001 months ago
BreatheSuite

Remote Registered Respiratory Therapist

BreatheSuite

Remote
Part-time
Remote1 months ago
Infosys Limited

Oracle ERP - Senior Program Lead

Infosys Limited

Remote
Full-time
Remote1 months ago
D-ploy

Mobile Device SME (MS Intune, Autopilot, Short-Term Project)

D-ploy

Contract
Remote1 months ago
TELUS

Disability Case Manager

TELUS

Full-time
Remote1 months ago
Caris MPI, Inc.

Account Executive - MI Clarity - North Carolina

Caris MPI, Inc.

Full-time
Remote1 months ago
ET

Software Development Team Leader | Work From Anywhere

evantis talent solutions

Remote
Full-time
RemoteTHB 90,000 - 100,0001 months ago
Health Care Service Corporation

Pharmacy Technician Representative (Work From Home)

Health Care Service Corporation

Full-time
RemoteUSD 18.46 - 37.841 months ago
24-MAG

Remote | India-Based Technical Customer Success Engineer — $25K–$40K/year

24-MAG

Remote
Full-time
RemoteUSD 25,000 - 40,0001 months ago
Triptastic Adventures

Remote Customer Relations Assistant

Triptastic Adventures

Remote
Full-time
Remote1 months ago
Kainos

Workday Financials Consultant (P2P)- Post-Deployment

Kainos

Remote
Full-time
Remote1 months ago
24-MAG

Remote | Tamil-English AI Response Evaluator — $10–$20/hour

24-MAG

Remote
Contract
RemoteUSD 10 - 201 months ago
TestPros

HIPAA Compliance Assessor/Consultant (Remote, Part-Time)

TestPros

Remote
Contract
RemoteUSD 50 - 851 months ago
Scale-X Solutions

Administrative and Social Media Virtual Assistant (AU Dayshift, WFH Philippines

Scale-X Solutions

Remote
Full-time
RemoteAUD 8 - 91 months ago
24-MAG

Remote | SOP & Process Improvement Evaluation Consultant — $70–$110/hour

24-MAG

Remote
Contract
RemoteUSD 70 - 1101 months ago
24-MAG

Remote | Compliance & Risk Expert — $75–$105/hour

24-MAG

Remote
Contract
RemoteUSD 60 - 751 months ago
24-MAG

Remote | Semiconductor, ASIC & RFIC Design Consultant — Up to $110/hour

24-MAG

Remote
Contract
RemoteUSD 110 - 1101 months ago
ShipIn Systems

Senior DevOps Engineer - Pakistan

ShipIn Systems

Full-time
Remote1 months ago
First American

Texas Agency Sales Representative

First American

Remote
Full-time
RemoteUSD 70,000 - 100,0001 months ago
Lumiere Systems

Digital Experience Journey Mapping Lead

Lumiere Systems

Full-time
Remote1 months ago
Showing 1192111940 of 12021 jobs

Remote Work in South Carolina

South Carolina's economic history is a story of remarkable transformation, from one of the most plantation-dependent colonial economies in the Americas to a modern state that has attracted more foreign direct investment per capita than almost anywhere in the country. The rice and indigo plantations of the Lowcountry, worked by enslaved African people — many brought directly from rice-growing regions of West Africa — made colonial South Carolina extraordinarily wealthy and shaped a plantation aristocracy whose cultural influence lingered long after the Civil War ended slavery.

Cotton replaced rice and indigo after Eli Whitney's gin made large-scale production economical, and the Upcountry piedmont became a major cotton-growing region through the nineteenth century. The cotton boom led to textile mills — South Carolina had more textile mills than any other Southern state by 1900 — and mill towns like Greenville, Spartanburg, and Rock Hill developed around the industry. The decline of American textile manufacturing in the late twentieth century hit South Carolina hard, but the state's aggressive industrial recruitment strategy turned adversity into opportunity.

BMW chose Spartanburg, South Carolina, as the location for its first North American manufacturing plant in 1992, beginning a wave of foreign automotive investment that transformed the Upstate region. Mercedes-Benz Vans, Volvo (with a plant near Berkeley County), and their respective supplier networks followed, along with Boeing, which built its second 787 Dreamliner final assembly plant in North Charleston in 2009 — the company's first aircraft manufacturing operation outside of the Pacific Northwest. General Electric operates large manufacturing facilities in the state.

The Mercedes-Benz Vans plant, Boeing's Charleston facility, and BMW's Spartanburg campus are now among the largest industrial employers in the state, and the supply chain networks around them have created thousands of additional jobs in precision manufacturing, logistics, and engineering services.

Charleston has emerged as a significant technology and financial services hub, attractwith a growing presence of companies like Blackbaud, Benefitfocus, and Automated Trading Desk. The city's historic beauty, warm climate, and water access make it highly attractive to professionals seeking an alternative to expensive coastal metros.

Remote work has been a significant driver of South Carolina's recent growth. The state has attracted remote workers from New York, New Jersey, and the Mid-Atlantic with its combination of no estate tax, warm climate, beautiful coastline, and increasingly good infrastructure. The Greenville-Spartanburg metro in particular has emerged as a remote work destination for professionals in technology, engineering, and finance.