Remote Jobs in South Carolina

Browse 11784 remote jobs available in South Carolina (SC).

Valenz

Sr. Analyst - Healthcare Analytics

Valenz

Remote
Full-time
Remote2 days ago
Bright Vision Technologies

Senior PeopleSoft Engineer

Bright Vision Technologies

Remote
Full-time
RemoteUSD 100,000 - 150,0002 days ago
IQVIA

Clinical Trial Safety Scientist (FSP - Permanent Home Based)

IQVIA

Remote
Full-time
Remote2 days ago
Clyde &

Legal Document Reviewer (Remote - Contract)

Clyde &

Remote
Contract
Remote2 days ago
IRIUM

ARQUITECTO/A DE INFRAESTRUCTURAS

IRIUM

Full-time
RemoteEUR 44,000 - 46,0002 days ago
CrewBloom

Client Services Representative

CrewBloom

Remote
Trending
Full-time
Remote2 days ago
Rochester Midland Corporation (RMC)

Field Service Engineer (Remote in Western NY)

Rochester Midland Corporation (RMC)

Full-time
RemoteUSD 85,000 - 95,0002 days ago
Grafana Labs

Senior FullStack Engineer - Grafana Cloud Observability| US | Remote

Grafana Labs

Remote
Full-time
United States (Remote)2 days ago
Pavago

Admissions Coordinator

Pavago

Remote
Full-time
Remote2 days ago
SailPoint

Staff Machine Learning Engineer

SailPoint

Remote
Full-time
RemoteUSD 149,200 - 251,5762 days ago
StandWithUs

Data Science Assistant

StandWithUs

Remote
Part-time
RemoteUSD 22 - 222 days ago
Huzzle

Account Executive - Laboratory Services

Huzzle

Remote
Full-time
Remote2 days ago
Bright Vision Technologies

Lead Backend Developer

Bright Vision Technologies

Remote
Full-time
RemoteUSD 80,000 - 95,0002 days ago
RBGlobal

Field Development Business Improvement Analyst

RBGlobal

Remote
Full-time
Remote2 days ago
Fairbanks Morse Defense

IT Systems Engineer - Continuous Improvement

Fairbanks Morse Defense

Full-time
RemoteUSD 113,000 - 169,0002 days ago
Bright Vision Technologies

Enterprise Storage Specialist

Bright Vision Technologies

Remote
Full-time
RemoteUSD 100,000 - 150,0002 days ago
EXADS

Technical Success Manager

EXADS

Remote
Full-time
Remote2 days ago
Humana

Senior Informaticist

Humana

Remote
Full-time
RemoteUSD 97,900 - 133,5002 days ago
BCD Travel

Asesor corporativo Senior (CO, Colombia, Virtual, Colombia, LATAM)

BCD Travel

Remote
Full-time
Remote2 days ago
Bright Vision Technologies

NLP AI Engineer

Bright Vision Technologies

Remote
Full-time
RemoteUSD 100,000 - 150,0002 days ago
Showing 361380 of 11784 jobs

Remote Work in South Carolina

South Carolina's economic history is a story of remarkable transformation, from one of the most plantation-dependent colonial economies in the Americas to a modern state that has attracted more foreign direct investment per capita than almost anywhere in the country. The rice and indigo plantations of the Lowcountry, worked by enslaved African people — many brought directly from rice-growing regions of West Africa — made colonial South Carolina extraordinarily wealthy and shaped a plantation aristocracy whose cultural influence lingered long after the Civil War ended slavery.

Cotton replaced rice and indigo after Eli Whitney's gin made large-scale production economical, and the Upcountry piedmont became a major cotton-growing region through the nineteenth century. The cotton boom led to textile mills — South Carolina had more textile mills than any other Southern state by 1900 — and mill towns like Greenville, Spartanburg, and Rock Hill developed around the industry. The decline of American textile manufacturing in the late twentieth century hit South Carolina hard, but the state's aggressive industrial recruitment strategy turned adversity into opportunity.

BMW chose Spartanburg, South Carolina, as the location for its first North American manufacturing plant in 1992, beginning a wave of foreign automotive investment that transformed the Upstate region. Mercedes-Benz Vans, Volvo (with a plant near Berkeley County), and their respective supplier networks followed, along with Boeing, which built its second 787 Dreamliner final assembly plant in North Charleston in 2009 — the company's first aircraft manufacturing operation outside of the Pacific Northwest. General Electric operates large manufacturing facilities in the state.

The Mercedes-Benz Vans plant, Boeing's Charleston facility, and BMW's Spartanburg campus are now among the largest industrial employers in the state, and the supply chain networks around them have created thousands of additional jobs in precision manufacturing, logistics, and engineering services.

Charleston has emerged as a significant technology and financial services hub, attractwith a growing presence of companies like Blackbaud, Benefitfocus, and Automated Trading Desk. The city's historic beauty, warm climate, and water access make it highly attractive to professionals seeking an alternative to expensive coastal metros.

Remote work has been a significant driver of South Carolina's recent growth. The state has attracted remote workers from New York, New Jersey, and the Mid-Atlantic with its combination of no estate tax, warm climate, beautiful coastline, and increasingly good infrastructure. The Greenville-Spartanburg metro in particular has emerged as a remote work destination for professionals in technology, engineering, and finance.