Remote Jobs in South Carolina

Browse 12540 remote jobs available in South Carolina (SC).

Airship

Strategic Partnerships & Alliances Director

Airship

Remote
Part-time
Remote - U.S.1 months ago
Power Digital Marketing

Marketing Operations Intern, Fall 2026

Power Digital Marketing

Remote
Full-time
Remote - United States1 months ago
Wayvia

Customer Support Specialist

Wayvia

Remote
Full-time
Remote, U.S.1 months ago
Power Digital Marketing

Email & SMS Marketing Intern, Fall 2026

Power Digital Marketing

Remote
Full-time
Remote - United States1 months ago
Backblaze

Director, Enterprise Support

Backblaze

Remote
Full-time
Remote - US1 months ago
Power Digital Marketing

Influencer Marketing Intern, Fall 2026

Power Digital Marketing

Remote
Full-time
Remote - United States1 months ago
PointClickCare

Manager Software Engineering

PointClickCare

Remote
Full-time
Remote - US1 months ago
Power Digital Marketing

Organic Social Media Intern, Fall 2026

Power Digital Marketing

Remote
Full-time
Remote - United States1 months ago
Power Digital Marketing

Fashion Marketing & Account Management Intern, Fall 2026

Power Digital Marketing

Remote
Full-time
Remote - United States1 months ago
Headspace

District of Columbia (DC) Remote Mental Health Licensed Therapist, 1099 Contractor

Headspace

Remote
Contract
Remote - United States1 months ago
Marqeta

Principal Software Engineer

Marqeta

Remote
Full-time
Remote, USA1 months ago
Power Digital Marketing

Affiliate Partnership Marketing Intern, Fall 2026

Power Digital Marketing

Remote
Part-time
Remote - United States1 months ago
Onit, Inc.

Global Account Manager

Onit, Inc.

Full-time
Remote - USA1 months ago
Sonatype

Azure DevOps Engineer

Sonatype

Remote
Full-time
US - Remote1 months ago
Marqeta

Lead Product Manager, Enterprise AI & Automation

Marqeta

Remote
Full-time
Remote, USA1 months ago
Natera

Senior Director Clinical Biomarkers, BioPharma Business Development

Natera

Remote
Full-time
San Francisco, CA; US Remote1 months ago
Lemon.io

Senior React Full-stack Developer

Lemon.io

Full-time
Anywhere in the World1 months ago
Natera

Customer Experience Associate (Temporary)

Natera

Remote
Full-time
US Remote1 months ago
Natera

Senior Manager, Operational Excellence and Process Engineering

Natera

Remote
Full-time
US Remote1 months ago
Natera

Quality Engineer

Natera

Remote
Full-time
US Remote1 months ago
Showing 1238112400 of 12540 jobs

Remote Work in South Carolina

South Carolina's economic history is a story of remarkable transformation, from one of the most plantation-dependent colonial economies in the Americas to a modern state that has attracted more foreign direct investment per capita than almost anywhere in the country. The rice and indigo plantations of the Lowcountry, worked by enslaved African people — many brought directly from rice-growing regions of West Africa — made colonial South Carolina extraordinarily wealthy and shaped a plantation aristocracy whose cultural influence lingered long after the Civil War ended slavery.

Cotton replaced rice and indigo after Eli Whitney's gin made large-scale production economical, and the Upcountry piedmont became a major cotton-growing region through the nineteenth century. The cotton boom led to textile mills — South Carolina had more textile mills than any other Southern state by 1900 — and mill towns like Greenville, Spartanburg, and Rock Hill developed around the industry. The decline of American textile manufacturing in the late twentieth century hit South Carolina hard, but the state's aggressive industrial recruitment strategy turned adversity into opportunity.

BMW chose Spartanburg, South Carolina, as the location for its first North American manufacturing plant in 1992, beginning a wave of foreign automotive investment that transformed the Upstate region. Mercedes-Benz Vans, Volvo (with a plant near Berkeley County), and their respective supplier networks followed, along with Boeing, which built its second 787 Dreamliner final assembly plant in North Charleston in 2009 — the company's first aircraft manufacturing operation outside of the Pacific Northwest. General Electric operates large manufacturing facilities in the state.

The Mercedes-Benz Vans plant, Boeing's Charleston facility, and BMW's Spartanburg campus are now among the largest industrial employers in the state, and the supply chain networks around them have created thousands of additional jobs in precision manufacturing, logistics, and engineering services.

Charleston has emerged as a significant technology and financial services hub, attractwith a growing presence of companies like Blackbaud, Benefitfocus, and Automated Trading Desk. The city's historic beauty, warm climate, and water access make it highly attractive to professionals seeking an alternative to expensive coastal metros.

Remote work has been a significant driver of South Carolina's recent growth. The state has attracted remote workers from New York, New Jersey, and the Mid-Atlantic with its combination of no estate tax, warm climate, beautiful coastline, and increasingly good infrastructure. The Greenville-Spartanburg metro in particular has emerged as a remote work destination for professionals in technology, engineering, and finance.