Remote Jobs in South Carolina

Browse 12672 remote jobs available in South Carolina (SC).

InfraCloud

Senior Spark QA Engineer

InfraCloud

Remote
Full-time
RemoteToday
Astrana Health

Manager - Data Engineering

Astrana Health

Remote
Full-time
RemoteUSD 140,000 - 160,000Today
Contently

Managing Editor (Freelance)

Contently

Part-time
RemoteToday
Receptive

Physician - ADHD Diagnosis and Treatment (Delaware)

Receptive

Remote
Contract
RemoteToday
Receptive

Physician - ADHD Diagnosis and Treatment (Connecticut)

Receptive

Remote
Contract
RemoteToday
Rep Data

Senior Accountant, Sales Tax & Treasury

Rep Data

Remote
Full-time
RemoteToday
#twiceasnice Recruiting

[REMOTE] Sales Executive - Pharma CRM

#twiceasnice Recruiting

Remote
Full-time
RemoteUSD 150,000 - 175,000Today
Astrana Health

Manager - Advanced Analytics

Astrana Health

Remote
Full-time
RemoteUSD 160,000 - 170,000Today
PureCars

Senior Dealer Success Manager

PureCars

Remote
Full-time
RemoteToday
Receptive

Physician - ADHD Diagnosis and Treatment (Kansas)

Receptive

Remote
Contract
RemoteToday
Gymdesk

Onboarding Specialist

Gymdesk

Remote
Trending
Contract
RemoteToday
Figure

Senior Marketing Manager, ABM

Figure

Full-time
RemoteUSD 118,800 - 178,200Today
Cupix

Technical Account Manager

Cupix

Full-time
RemoteToday
Receptive

Physician - ADHD Diagnosis and Treatment (Missouri)

Receptive

Remote
Contract
RemoteToday
ICON plc

Clinical Research Associate

ICON plc

Remote
Full-time
RemoteToday
Docsumo

Senior Business Development Representative (3+ years, B2B SaaS Sales)

Docsumo

Full-time
RemoteToday
Stripe

Product Manager, ML Foundations and GenAI

Stripe

Remote
Full-time
RemoteToday
Boston Imaging

Field Service Engineer, Ultrasound (Southeast)

Boston Imaging

Full-time
RemoteToday
Arista Networks

Senior Software Engineer - C++ - Platform - Romania

Arista Networks

Remote
Full-time
RemoteToday
Canvas Medical

Developer Advocate

Canvas Medical

Remote
Full-time
RemoteUSD 150,000 - 190,000Today
Showing 141–160 of 12672 jobs

Remote Work in South Carolina

South Carolina's economic history is a story of remarkable transformation, from one of the most plantation-dependent colonial economies in the Americas to a modern state that has attracted more foreign direct investment per capita than almost anywhere in the country. The rice and indigo plantations of the Lowcountry, worked by enslaved African people — many brought directly from rice-growing regions of West Africa — made colonial South Carolina extraordinarily wealthy and shaped a plantation aristocracy whose cultural influence lingered long after the Civil War ended slavery.

Cotton replaced rice and indigo after Eli Whitney's gin made large-scale production economical, and the Upcountry piedmont became a major cotton-growing region through the nineteenth century. The cotton boom led to textile mills — South Carolina had more textile mills than any other Southern state by 1900 — and mill towns like Greenville, Spartanburg, and Rock Hill developed around the industry. The decline of American textile manufacturing in the late twentieth century hit South Carolina hard, but the state's aggressive industrial recruitment strategy turned adversity into opportunity.

BMW chose Spartanburg, South Carolina, as the location for its first North American manufacturing plant in 1992, beginning a wave of foreign automotive investment that transformed the Upstate region. Mercedes-Benz Vans, Volvo (with a plant near Berkeley County), and their respective supplier networks followed, along with Boeing, which built its second 787 Dreamliner final assembly plant in North Charleston in 2009 — the company's first aircraft manufacturing operation outside of the Pacific Northwest. General Electric operates large manufacturing facilities in the state.

The Mercedes-Benz Vans plant, Boeing's Charleston facility, and BMW's Spartanburg campus are now among the largest industrial employers in the state, and the supply chain networks around them have created thousands of additional jobs in precision manufacturing, logistics, and engineering services.

Charleston has emerged as a significant technology and financial services hub, attractwith a growing presence of companies like Blackbaud, Benefitfocus, and Automated Trading Desk. The city's historic beauty, warm climate, and water access make it highly attractive to professionals seeking an alternative to expensive coastal metros.

Remote work has been a significant driver of South Carolina's recent growth. The state has attracted remote workers from New York, New Jersey, and the Mid-Atlantic with its combination of no estate tax, warm climate, beautiful coastline, and increasingly good infrastructure. The Greenville-Spartanburg metro in particular has emerged as a remote work destination for professionals in technology, engineering, and finance.